Persistence of abnormalities in white matter in children with type 1 diabetes

Aims/hypothesis Prior studies suggest white matter growth is reduced and white matter microstructure is altered in the brains of young children with type 1 diabetes when compared with brains of non-diabetic children, due in part to adverse effects of hyperglycaemia. This longitudinal observational s...

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Veröffentlicht in:	Diabetologia 2018-07, Vol.61 (7), p.1538-1547
Hauptverfasser:	Fox, Larry A., Hershey, Tamara, Mauras, Nelly, Arbeláez, Ana Maria, Tamborlane, William V., Buckingham, Bruce, Tsalikian, Eva, Englert, Kim, Raman, Mira, Jo, Booil, Shen, Hanyang, Reiss, Allan, Mazaika, Paul
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Factors Anisotropy Attention deficit hyperactivity disorder Biomarkers - blood Blood Glucose - metabolism Case-Control Studies Child Child Development Child, Preschool Children Cognitive ability Cognitive Dysfunction - etiology Diabetes Diabetes mellitus Diabetes mellitus (insulin dependent) Diabetes Mellitus, Type 1 - blood Diabetes Mellitus, Type 1 - complications Diabetes Mellitus, Type 1 - diagnosis Diffusion Tensor Imaging Female Glucose monitoring Glycated Hemoglobin A - metabolism Human Physiology Humans Hyperglycemia Internal Medicine Leukoencephalopathies - diagnostic imaging Leukoencephalopathies - etiology Leukoencephalopathies - physiopathology Longitudinal Studies Magnetic Resonance Imaging Male Medicine Medicine & Public Health Metabolic Diseases Neurological disorders Pediatrics Prognosis Risk Factors Substantia alba Time Factors United States
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