Preoperative Prognostic Nutritional Index Predicts Long-Term Surgical Outcomes in Patients with Esophageal Squamous Cell Carcinoma

Background The purpose of the present study is to investigate the utility of prognostic nutritional index (PNI) as a simple and readily available marker in esophageal squamous cell carcinoma (ESCC). Methods We retrospectively analyzed 169 patients who underwent potentially curative esophagectomy, fo...

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Veröffentlicht in:	World journal of surgery 2018-07, Vol.42 (7), p.2199-2208
Hauptverfasser:	Hirahara, Noriyuki, Tajima, Yoshitsugu, Fujii, Yusuke, Kaji, Shunsuke, Yamamoto, Tetsu, Hyakudomi, Ryoji, Taniura, Takahito, Miyazaki, Yoshiko, Kishi, Takashi, Kawabata, Yasunari
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdominal Surgery Cardiac Surgery Esophageal cancer Esophagus General Surgery Geriatrics Medicine Medicine & Public Health Nutrition assessment Older people Original Scientific Report Patients Regression analysis Risk factors Squamous cell carcinoma Surgery Survival Thoracic Surgery Vascular Surgery
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Zusammenfassung:	Background The purpose of the present study is to investigate the utility of prognostic nutritional index (PNI) as a simple and readily available marker in esophageal squamous cell carcinoma (ESCC). Methods We retrospectively analyzed 169 patients who underwent potentially curative esophagectomy, for histologically verified ESCC. We decided to set the optimal cutoff value for preoperative PNI levels at 49.2, based on the cancer-specific survival (CSS) and the overall survival (OS) by receiver operating characteristic curve analysis. Results Multivariate logistic regression analysis identified that TNM pStage III [hazard ratio (HR) 3.261, p
ISSN:	0364-2313 1432-2323
DOI:	10.1007/s00268-017-4437-1