Dynamics of sister chromatids through the cell cycle: Together and apart

Dynamics of sister chromatids through the cell cycle: Together and apart

When and how sister chromatid resolution occurs after DNA replication is a fundamental question. Stanyte et al. (2018. https://doi.org/10.1083/jcb.201801157) used CRISPR/Cas9 technology to label and track genomic loci in live cells throughout the cell cycle, shedding light on how replication is link...

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Veröffentlicht in:The Journal of cell biology 2018-06, Vol.217 (6), p.1887-1889
Hauptverfasser: Takahashi, Motoko, Hirota, Toru
Format: Artikel
Sprache:eng
Schlagworte:
Cell cycle
Cell division
Cellular biology
Chromatids
Commentaries
CRISPR
Deoxyribonucleic acid
DNA
DNA biosynthesis
Genomes
Mitosis
Propagation
Replication
Sister chromatids
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Zusammenfassung:When and how sister chromatid resolution occurs after DNA replication is a fundamental question. Stanyte et al. (2018. https://doi.org/10.1083/jcb.201801157) used CRISPR/Cas9 technology to label and track genomic loci in live cells throughout the cell cycle, shedding light on how replication is linked to mitotic sister chromatid organization.
ISSN:0021-9525
1540-8140
DOI:10.1083/jcb.201804091