Characteristics and Outcomes of Influenza-Associated Encephalopathy Cases Among Children and Adults in Japan, 2010-2015

Influenza-associated encephalopathy (IAE) can result in severe neurologic disease with high mortality. Most IAE cases are reported among children worldwide. Understanding of IAE among adults is limited. Data were collected on IAE cases reported through the National Epidemiological Surveillance of In...

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Veröffentlicht in:Clinical infectious diseases 2018-06, Vol.66 (12), p.1831-1837
Hauptverfasser: Okuno, Hideo, Yahata, Yuichiro, Tanaka-Taya, Keiko, Arai, Satoru, Satoh, Hiroshi, Morino, Saeko, Shimada, Tomoe, Sunagawa, Tomimasa, Uyeki, Timothy M, Oishi, Kazunori
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Sprache:eng
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Zusammenfassung:Influenza-associated encephalopathy (IAE) can result in severe neurologic disease with high mortality. Most IAE cases are reported among children worldwide. Understanding of IAE among adults is limited. Data were collected on IAE cases reported through the National Epidemiological Surveillance of Infectious Diseases database in Japan from 2010 through 2015. IAE cases were stratified by age category and analyzed using descriptive statistics to assess differences in characteristics and outcomes. Among 385 IAE cases, median age at diagnosis was 7 years (range, 0-90), and 283 (74%) were aged
ISSN:1058-4838
1537-6591
DOI:10.1093/cid/cix1126