Electrically controlled drug release using pH-sensitive polymer films

Electrically controlled drug release using pH-sensitive polymer films

Drug delivery systems (DDS) that allow spatially and temporally controlled release of drugs are of particular interest in the field of drug delivery. These systems create opportunities for individually tailored doses of drugs to be administered as well as reduce side effects by localizing the initia...

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Veröffentlicht in:Nanoscale 2018-05, Vol.10 (21), p.10087-10093
Hauptverfasser: Neumann, S Ephraim, Chamberlayne, Christian F, Zare, Richard N
Format: Artikel
Sprache:eng
Schlagworte:
Biocompatibility
Biomedical materials
Chitosan
Controlled release
Curcumin
Drug Delivery Systems
Drug Liberation
Fluorescein
Hydrogen-Ion Concentration
Hydrophobicity
Hypoglycemia
Insulin
Meloxicam
Methacrylic acid
Molecular chains
Nanocomposites
Polymer films
Polymers
Polymethacrylic Acids
Polymethyl methacrylate
Saline solutions
Side effects
Solubility
Surgical implants
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Beschreibung
Zusammenfassung:Drug delivery systems (DDS) that allow spatially and temporally controlled release of drugs are of particular interest in the field of drug delivery. These systems create opportunities for individually tailored doses of drugs to be administered as well as reduce side effects by localizing the initial drug dose to the organ of interest. We present an electroresponsive DDS in the form of a bioresorbable nanocomposite film which operates at low voltages (
ISSN:2040-3364
2040-3372
DOI:10.1039/c8nr02602e