Blood pressure and mortality in a prospective cohort of HIV-infected adults in Port-au-Prince, Haiti

OBJECTIVE:The objective of this study was to determine how baseline blood pressure and incident hypertension related to antiretroviral therapy (ART) initiation, HIV-related inflammation and mortality in HIV-infected adults in a low-income country. METHODS:We conducted long-term follow-up of HIV-infe...

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Veröffentlicht in:	Journal of hypertension 2018-07, Vol.36 (7), p.1533-1539
Hauptverfasser:	Batavia, Ashita S, Severe, Patrice, Lee, Myung Hee, Apollon, Alexandra, Zhu, Yuan Shan, Dupnik, Kathryn M, McNairy, Margaret L, Pape, Jean W, Fitzgerald, Daniel W, Peck, Robert N
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age Factors Anti-HIV Agents - therapeutic use Blood Pressure Body Mass Index CD4 Lymphocyte Count Developing Countries Female Follow-Up Studies Haiti - epidemiology HIV Infections - complications HIV Infections - drug therapy HIV Infections - immunology HIV Infections - mortality Humans Hypertension - epidemiology Hypertension - physiopathology Incidence Inflammation - blood Inflammation - virology Interleukin-6 - blood Male Middle Aged Prevalence Proportional Hazards Models Prospective Studies Time-to-Treatment
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Zusammenfassung:	OBJECTIVE:The objective of this study was to determine how baseline blood pressure and incident hypertension related to antiretroviral therapy (ART) initiation, HIV-related inflammation and mortality in HIV-infected adults in a low-income country. METHODS:We conducted long-term follow-up of HIV-infected adults who had participated in a trial of early vs. delayed initiation of ART in Port-au-Prince, Haiti. Between 2005 and 2008, 816 HIV-infected adults were randomized to early (N = 408) vs. delayed ART (when CD4 cell count
ISSN:	0263-6352 1473-5598
DOI:	10.1097/HJH.0000000000001723