Failure of Azithromycin 2.0 g in the Treatment of Gonococcal Urethritis Caused by High-Level Resistance in California

We report a treatment failure to azithromycin 2.0 g caused by a urethral Neisseria gonorrhoeae isolate with high-level azithromycin resistance in California. This report describes the epidemiological case investigation and phenotypic and genetic characterization of the treatment failure isolate.

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Veröffentlicht in:Sexually transmitted diseases 2015-05, Vol.42 (5), p.279-280
Hauptverfasser: Gose, Severin O., Soge, Olusegun O., Beebe, James L., Nguyen, Duylinh, Stoltey, Juliet E., Bauer, Heidi M.
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container_end_page 280
container_issue 5
container_start_page 279
container_title Sexually transmitted diseases
container_volume 42
creator Gose, Severin O.
Soge, Olusegun O.
Beebe, James L.
Nguyen, Duylinh
Stoltey, Juliet E.
Bauer, Heidi M.
description We report a treatment failure to azithromycin 2.0 g caused by a urethral Neisseria gonorrhoeae isolate with high-level azithromycin resistance in California. This report describes the epidemiological case investigation and phenotypic and genetic characterization of the treatment failure isolate.
doi_str_mv 10.1097/OLQ.0000000000000265
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source MEDLINE; Applied Social Sciences Index & Abstracts (ASSIA); JSTOR Archive Collection A-Z Listing
subjects Adult
Anti-Bacterial Agents - administration & dosage
Antibiotics
Azithromycin - pharmacology
California - epidemiology
Ceftriaxone - administration & dosage
Contact Tracing
Drug resistance
Drug Resistance, Bacterial
Epidemiology
Female
Genetics
Genotype & phenotype
Gonorrhea
Gonorrhea - drug therapy
Gonorrhea - genetics
Gonorrhea - microbiology
Humans
Male
Microbial Sensitivity Tests
Neisseria gonorrhoeae - drug effects
Neisseria gonorrhoeae - genetics
Population Surveillance
Treatment Failure
United States - epidemiology
Urethritis - drug therapy
Urethritis - etiology
Urethritis - genetics
title Failure of Azithromycin 2.0 g in the Treatment of Gonococcal Urethritis Caused by High-Level Resistance in California
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