Combination of Amphotericin B and Terbinafine against Melanized Fungi Associated with Chromoblastomycosis

Combination of Amphotericin B and Terbinafine against Melanized Fungi Associated with Chromoblastomycosis

Our studies showed that a combination of amphotericin B and terbinafine had synergistic effects against the majority of melanized fungi associated with chromoblastomycosis (CBM) and similar infections, including those with , , , , , , , and This drug combination could provide an option for the treat...

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Veröffentlicht in:Antimicrobial agents and chemotherapy 2018-06, Vol.62 (6)
Hauptverfasser: Deng, S, Lei, W, de Hoog, G S, Yang, L, Vitale, R G, Rafati, H, Seyedmousavi, M, Tolooe, A, van der Lee, H, Liao, W, Verweij, P E, Seyedmousavi, S
Format: Artikel
Sprache:eng
Schlagworte:
Amphotericin B
Antifungal Agents
Chromoblastomycosis
Pharmacology
Terbinafine
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Zusammenfassung:Our studies showed that a combination of amphotericin B and terbinafine had synergistic effects against the majority of melanized fungi associated with chromoblastomycosis (CBM) and similar infections, including those with , , , , , , , and This drug combination could provide an option for the treatment of severe or unresponsive cases of CBM, particularly in cases due to species of and .
ISSN:0066-4804
1098-6596
DOI:10.1128/AAC.00270-18