Effect of Maternal Smoking on Plasma and Urinary Measures of Vitamin E Isoforms in the First Month after Extreme Preterm Birth

Effect of Maternal Smoking on Plasma and Urinary Measures of Vitamin E Isoforms in the First Month after Extreme Preterm Birth

We examined the effect of maternal smoking on plasma and urinary levels of vitamin E isoforms in preterm infants. Maternal smoking during pregnancy decreased infant plasma alpha- and gamma-tocopherol concentrations at 1 week and 4 weeks, with 45% of infants of smokers deficient in alpha-tocopherol a...

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Veröffentlicht in:The Journal of pediatrics 2018-06, Vol.197, p.280-285.e3
Hauptverfasser: Stone, Cosby, Qiu, Yunping, Kurland, Irwin J., Slaughter, James C., Moore, Paul, Cook-Mills, Joan, Hartert, Tina, Aschner, Judy L.
Format: Artikel
Sprache:eng
Schlagworte:
Adult
alpha-tocopherol
Biomarkers - metabolism
Female
gamma-tocopherol
Humans
Infant, Extremely Premature - metabolism
Infant, Newborn
Male
Oxidative Stress - physiology
Pregnancy
prematurity
Prenatal Exposure Delayed Effects - metabolism
preterm
Prospective Studies
Risk Factors
smoking
Smoking - adverse effects
vitamin E
Vitamin E - metabolism
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Zusammenfassung:We examined the effect of maternal smoking on plasma and urinary levels of vitamin E isoforms in preterm infants. Maternal smoking during pregnancy decreased infant plasma alpha- and gamma-tocopherol concentrations at 1 week and 4 weeks, with 45% of infants of smokers deficient in alpha-tocopherol at 1 month after birth.
ISSN:0022-3476
1097-6833
DOI:10.1016/j.jpeds.2017.12.062