Evaluating the Efficacy of Xylitol Wipes on Cariogenic Bacteria in 19- to 35-month-old Children: A Double-blind Randomized Controlled Trial

Dental caries is an infectious disease with as the main cariogenic bacteria. Children with early S. colonization have a higher risk of developing dental caries than those with later colonization. Therefore, prevention or delay of S. colonization may be advantageous for the prevention of early childhood caries (ECC). To evaluate and compare the effectiveness of xylitol and placebo wipes on S. count in 19- to 35-month-old children. Forty-four children were randomly selected from a daycare center and divided into two groups. Allocation concealment was done and both (placebo and xylitol) wipes were distributed to their parents. Instructions were given regarding their use, to be used twice daily for 2 weeks and the S. levels in the saliva were enumerated before and after wipes usage. The collected data were tabulated and statistically analyzed using paired and unpaired t-tests. A clinically significant decrease in the S. count was observed in the xylitol wipes group than the placebo wipes group. Intergroup comparison results were found to be statistically insignificant. Xylitol wipes usage could serve as a useful adjunct in reducing the cariogenic bacteria, especially and thus can be considered as an adjunct oral hygiene tool for caries prevention in young children Kayalvizhi G, Nivedha D, Sajeev R, Prathima GS, Suganya M, Ramesh V. Evaluating the Efficacy of Xylitol Wipes on Cariogenic Bacteria in 19- to 35-month-old Children: A Double-blind Randomized Controlled Trial. Int J Clin Pediatr Dent 2018;11(1):13-17.