Uric acid and obesity-related phenotypes in postmenopausal women

Uric acid and obesity-related phenotypes in postmenopausal women

The aim of this study was to find the genetic, metabolic, and nutritional risk factors, which can be associated with uric acid (UA) level. The risk factors related to uricemia were assessed among 271 postmenopausal women without cardiometabolic disorders and hypolipidemic/hypoglycemic treatment sele...

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Veröffentlicht in:Molecular and cellular biochemistry 2018-06, Vol.443 (1-2), p.111-119
Hauptverfasser: Grygiel-Górniak, B., Mosor, M., Marcinkowska, J., Przysławski, J., Nowak, J.
Format: Artikel
Sprache:eng
Schlagworte:
Adrenergic receptors
Aged
Biochemistry
Biomedical and Life Sciences
Blood pressure
Body fat
Body mass index
Body size
Body weight
Cardiology
Dietary fat
Disorders
Female
Genetic analysis
Genetic aspects
Glucose
Health risk assessment
High density
Homeostasis
Humans
Hyperglycemia
Hypertriglyceridemia
Insulin
Insulin resistance
Life Sciences
Medical Biochemistry
Medical research
Metabolism
Middle Aged
Obesity
Obesity - blood
Obesity - genetics
Oncology
Overweight
Peroxisome proliferator-activated receptors
Phenotype
Polymorphism
Polymorphism, Genetic
Post-menopause
Postmenopausal women
Postmenopause - blood
Postmenopause - genetics
PPAR gamma - genetics
Receptors, Adrenergic, beta-1 - genetics
Regression analysis
Regression models
Residential density
Risk analysis
Risk factors
Triglycerides
Uric acid
Uric Acid - blood
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Beschreibung
Zusammenfassung:The aim of this study was to find the genetic, metabolic, and nutritional risk factors, which can be associated with uric acid (UA) level. The risk factors related to uricemia were assessed among 271 postmenopausal women without cardiometabolic disorders and hypolipidemic/hypoglycemic treatment selected from a cohort of 1423 obese postmenopausal women. The bioimpedance analysis and biochemical and genetic analyses were performed in two groups characterized by serum UA ≥ 4 mg/dL (238 μmol/L) and 
ISSN:0300-8177
1573-4919
DOI:10.1007/s11010-017-3215-6