An observational, epidemiological study on pattern of clinical presentation and associated laboratory findings in patients of premature hair graying

After taking informed consent, a detailed clinical history and laboratory investigations (including complete blood count, iron studies, thyroid function test, and serum Vitamin B12 levels) were done. [...]low serum levels of Vitamin B12 are also considered as one of the causes for premature graying. Most of the patients (19%) with low serum Vitamin B12 levels had normal value of hemoglobin. [...]these patients need to be further investigated for vitamin B12 deficiency even in the absence of anemia.