The role of the Acute Cystitis Symptom Score questionnaire for research and antimicrobial stewardship. Validation of the Hungarian version

A very similar pattern was found, when patient-reported outcome was assessed earlier using the Russian and Uzbek versions of the ACSS [13]. Since 'Typical' domain have shown excellent results concerning sensitivity and specificity for diagnosing AC (the cut-off score of 6), it may be reasonable to use the same domain at a score of 1 for patient-reported outcome of success of treatment. Broader spectrum antibiotics, such as carbapenems, fluoroquinolones or cephalosporins, however, should be saved for patients with more severe infections, whereas patients with benign infections like AC should be treated initially with narrow spectrum antibiotics in accordance with the actual guidelines, availability and local patterns of susceptibility [2]. [...]fast and unequivocal diagnosis and outcome assessment of uncomplicated AC is extremely important both for clinical and research purposes. [...]the similarity of results of the current study to those of previous studies, may judge that the effect of possible selection bias if any, is however non-significant and the results are representative. [...]high sensitivity, specificity, association between laboratory tests and questionnaire results, the clear difference in scores between control group and patient group, all these together suggest, that the questionnaire is able to describe the dynamics of the clinical condition very well. In our study, we have validated the Hungarian version of the ACSS not only linguistically but also clinically. [...]the Hungarian ACSS can now be used as an effective tool in the diagnosis and outcome assessment of AC in Hungarian speaking women for clinical and research purposes not only by urologists, but also by gynaecologists and general practitioners in their clinical practice.