Detection of 23 Gastrointestinal Pathogens Among Children Who Present With Diarrhea

Key Points In the era of widespread rotavirus vaccine use, toxigenic Clostridium difficile, diarrheagenic Escherichia coli, and viruses (particularly norovirus) are commonly detected among children with infectious gastroenteritis in the United States by using a multipathogen molecular panel. Abstract Background Diarrheal diseases are a major cause of ambulatory care visits and hospitalizations among children. Because of overlapping signs and symptoms and expensive and inefficient testing methods, the etiology of pediatric diarrhea is rarely established. Methods We identified children