Feature selection of ultrahigh-dimensional covariates with survival outcomes: a selective review

Many modern biomedical studies have yielded survival data with high-throughput predictors. The goals of scientific research often lie in identifying predictive biomarkers, understanding biological mechanisms and making accurate and precise predictions. Variable screening is a crucial first step in a...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Applied Mathematics-A Journal of Chinese Universities 2017-12, Vol.32 (4), p.379-396
Hauptverfasser: Hong, Hyokyoung Grace, Li, Yi
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Many modern biomedical studies have yielded survival data with high-throughput predictors. The goals of scientific research often lie in identifying predictive biomarkers, understanding biological mechanisms and making accurate and precise predictions. Variable screening is a crucial first step in achieving these goals. This work conducts a selective review of feature screening procedures for survival data with ultrahigh dimensional covariates. We present the main methodologies, along with the key conditions that ensure sure screening properties. The practical utility of these methods is examined via extensive simulations. We conclude the review with some future opportunities in this field.
ISSN:1005-1031
1000-4424
1993-0445
DOI:10.1007/s11766-017-3547-8