Effect of local application of curcumin and ornidazole gel in chronic periodontitis patients

Objective: The objective of this study is to evaluate the comparative effect of curcumin and ornidazole in treating chronic periodontitis. Materials and Methods: Twenty individuals of both sexes aged between 27 and 53 years diagnosed with chronic periodontitis and having pocket depths >5 mm bilat...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:International Journal of Pharmaceutical Investigation 2017-10, Vol.7 (4), p.188-192
Hauptverfasser: Ravishankar, P, Kumar, Y, Anila, E, Chakraborty, Priyankar, Malakar, Maharshi, Mahalakshmi, R
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Objective: The objective of this study is to evaluate the comparative effect of curcumin and ornidazole in treating chronic periodontitis. Materials and Methods: Twenty individuals of both sexes aged between 27 and 53 years diagnosed with chronic periodontitis and having pocket depths >5 mm bilaterally were selected for this study, in a split-mouth design. Examination of plaque index, probing pocket depth, and clinical attachment level was measured for each patient. The patients received a complete prophylaxis including scaling and root planing after which, both test gels were injected into the two experimental sites chosen, that had probing depth (PD) >5 mm and were located in symmetric quadrants. Pocket PD, clinical attachment loss, and plaque index were recorded at days 0 and 30. Results: At 1-month evaluation, curcumin group showed a significant decrease in pocket PD, plaque index, and clinical attachment loss when compared to the ornidazole group. Conclusion: The results show a more favorable outcome with curcumin than ornidazole gel, thus curcumin can be used as an adjunct to nonsurgical periodontal therapy.
ISSN:2230-973X
2230-9713
DOI:10.4103/jphi.JPHI_82_17