The IDA3 adapter, required for intraflagellar transport of I1 dynein, is regulated by ciliary length

We determined how the ciliary motor I1 dynein is transported. A specialized adapter, IDA3, facilitates I1 dynein attachment to the ciliary transporter called intraflagellar transport (IFT). Loading of IDA3 and I1 dynein on IFT is regulated by ciliary length.

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Veröffentlicht in:Molecular biology of the cell 2018-04, Vol.29 (8), p.886-896
Hauptverfasser: Hunter, Emily L, Lechtreck, Karl, Fu, Gang, Hwang, Juyeon, Lin, Huawen, Gokhale, Avanti, Alford, Lea M, Lewis, Brian, Yamamoto, Ryosuke, Kamiya, Ritsu, Yang, Fan, Nicastro, Daniela, Dutcher, Susan K, Wirschell, Maureen, Sale, Winfield S
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container_end_page 896
container_issue 8
container_start_page 886
container_title Molecular biology of the cell
container_volume 29
creator Hunter, Emily L
Lechtreck, Karl
Fu, Gang
Hwang, Juyeon
Lin, Huawen
Gokhale, Avanti
Alford, Lea M
Lewis, Brian
Yamamoto, Ryosuke
Kamiya, Ritsu
Yang, Fan
Nicastro, Daniela
Dutcher, Susan K
Wirschell, Maureen
Sale, Winfield S
description We determined how the ciliary motor I1 dynein is transported. A specialized adapter, IDA3, facilitates I1 dynein attachment to the ciliary transporter called intraflagellar transport (IFT). Loading of IDA3 and I1 dynein on IFT is regulated by ciliary length.
doi_str_mv 10.1091/mbc.E17-12-0729
format Article
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title The IDA3 adapter, required for intraflagellar transport of I1 dynein, is regulated by ciliary length
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