The IDA3 adapter, required for intraflagellar transport of I1 dynein, is regulated by ciliary length
We determined how the ciliary motor I1 dynein is transported. A specialized adapter, IDA3, facilitates I1 dynein attachment to the ciliary transporter called intraflagellar transport (IFT). Loading of IDA3 and I1 dynein on IFT is regulated by ciliary length.
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Veröffentlicht in: | Molecular biology of the cell 2018-04, Vol.29 (8), p.886-896 |
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container_title | Molecular biology of the cell |
container_volume | 29 |
creator | Hunter, Emily L Lechtreck, Karl Fu, Gang Hwang, Juyeon Lin, Huawen Gokhale, Avanti Alford, Lea M Lewis, Brian Yamamoto, Ryosuke Kamiya, Ritsu Yang, Fan Nicastro, Daniela Dutcher, Susan K Wirschell, Maureen Sale, Winfield S |
description | We determined how the ciliary motor I1 dynein is transported. A specialized adapter, IDA3, facilitates I1 dynein attachment to the ciliary transporter called intraflagellar transport (IFT). Loading of IDA3 and I1 dynein on IFT is regulated by ciliary length. |
doi_str_mv | 10.1091/mbc.E17-12-0729 |
format | Article |
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title | The IDA3 adapter, required for intraflagellar transport of I1 dynein, is regulated by ciliary length |
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