The IDA3 adapter, required for intraflagellar transport of I1 dynein, is regulated by ciliary length

The IDA3 adapter, required for intraflagellar transport of I1 dynein, is regulated by ciliary length

We determined how the ciliary motor I1 dynein is transported. A specialized adapter, IDA3, facilitates I1 dynein attachment to the ciliary transporter called intraflagellar transport (IFT). Loading of IDA3 and I1 dynein on IFT is regulated by ciliary length.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Molecular biology of the cell 2018-04, Vol.29 (8), p.886-896
Hauptverfasser: Hunter, Emily L, Lechtreck, Karl, Fu, Gang, Hwang, Juyeon, Lin, Huawen, Gokhale, Avanti, Alford, Lea M, Lewis, Brian, Yamamoto, Ryosuke, Kamiya, Ritsu, Yang, Fan, Nicastro, Daniela, Dutcher, Susan K, Wirschell, Maureen, Sale, Winfield S
Format: Artikel
Sprache:eng
Schlagworte:
Brief Report
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:We determined how the ciliary motor I1 dynein is transported. A specialized adapter, IDA3, facilitates I1 dynein attachment to the ciliary transporter called intraflagellar transport (IFT). Loading of IDA3 and I1 dynein on IFT is regulated by ciliary length.
ISSN:1059-1524
1939-4586
DOI:10.1091/mbc.E17-12-0729