Predicting sperm retrieval rates in testicular sperm extraction for azoospermia according to endocrine profiles
Background and Aims: The present study was carried out to examine the predictive value of endocrine profiles as indicators of the sperm retrieval rate on testicular sperm extraction (TESE) in azoospermic men. Methods: Prior to TESE, the serum levels of follicle stimulating hormone (FSH), luteinizi...
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| Veröffentlicht in: | Reproductive medicine and biology 2005-12, Vol.4 (4), p.239-245 |
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| creator | JINNO, MASAO OZAKI, TSUNEO NAKAMURA, YUKIO IWASHITA, MITSUTOSHI |
| description | Background and Aims: The present study was carried out to examine the predictive value of endocrine profiles as indicators of the sperm retrieval rate on testicular sperm extraction (TESE) in azoospermic men.
Methods: Prior to TESE, the serum levels of follicle stimulating hormone (FSH), luteinizing hormone (LH), prolactin, testosterone, dihydrotestosterone (DHT), estradiol and 17 α‐hydroxyprogesterone were measured and the sagittal cross‐sections of the testis were acquired using ultrasonography.
Results: The sperm retrieval rates according to the cause of azoospermia were 40% for idiopathic azoospermia, and 100% for obstructive azoospermia, cryptorchidsm and ejaculatory disorder. Based on the endocrinological profiles, the sperm retrieval rates showed significant differences at 100% for FSH 15 mIU/mL or LH 2 mIU/mL, 0% for FSH > 60 mIU/mL or LH > 12 mIU/mL, and 33% for the intermediate groups (P < 0.01). Comparison of the retrieval of spermatozoa and serum DHT level for the intermediate group also showed a significant difference, with retrieval rates of 58% for DHT 0.5 ng/mL and 0% for DHT > 0.5 ng/mL (P |
| doi_str_mv | 10.1111/j.1447-0578.2005.00113.x |
| format | Article |
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Methods: Prior to TESE, the serum levels of follicle stimulating hormone (FSH), luteinizing hormone (LH), prolactin, testosterone, dihydrotestosterone (DHT), estradiol and 17 α‐hydroxyprogesterone were measured and the sagittal cross‐sections of the testis were acquired using ultrasonography.
Results: The sperm retrieval rates according to the cause of azoospermia were 40% for idiopathic azoospermia, and 100% for obstructive azoospermia, cryptorchidsm and ejaculatory disorder. Based on the endocrinological profiles, the sperm retrieval rates showed significant differences at 100% for FSH 15 mIU/mL or LH 2 mIU/mL, 0% for FSH > 60 mIU/mL or LH > 12 mIU/mL, and 33% for the intermediate groups (P < 0.01). Comparison of the retrieval of spermatozoa and serum DHT level for the intermediate group also showed a significant difference, with retrieval rates of 58% for DHT 0.5 ng/mL and 0% for DHT > 0.5 ng/mL (P < 0.01).
Conclusions: The etiology, serum FSH, LH and DHT levels are useful in predicting the sperm retrieval rates on TESE in azoospermic patients. (Reprod Med Biol 2005; 4: 239–245)</description><identifier>ISSN: 1445-5781</identifier><identifier>EISSN: 1447-0578</identifier><identifier>DOI: 10.1111/j.1447-0578.2005.00113.x</identifier><identifier>PMID: 29662394</identifier><language>eng</language><publisher>Melbourne, Australia: Blackwell Science Pty</publisher><subject>17β-Estradiol ; Andrology ; azoospermia ; Dihydrotestosterone ; endocrinology ; etiology ; Follicle-stimulating hormone ; Follicles ; In vitro fertilization ; Luteinizing hormone ; Ovaries ; Prolactin ; Serum levels ; Sperm ; sperm retrieval rate ; Testes ; testicular sperm extraction ; Testosterone ; Urology</subject><ispartof>Reproductive medicine and biology, 2005-12, Vol.4 (4), p.239-245</ispartof><rights>2005. This work is published under https://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4693-a9379150d559ca39f9c425299632f1effb907599506a9e2b4e41864943526b493</citedby><cites>FETCH-LOGICAL-c4693-a9379150d559ca39f9c425299632f1effb907599506a9e2b4e41864943526b493</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891751/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891751/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,864,885,1416,11553,27915,27916,45565,45566,46043,46467,53782,53784</link.rule.ids><linktorsrc>$$Uhttps://onlinelibrary.wiley.com/doi/abs/10.1111%2Fj.1447-0578.2005.00113.x$$EView_record_in_Wiley-Blackwell$$FView_record_in_$$GWiley-Blackwell</linktorsrc><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29662394$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>JINNO, MASAO</creatorcontrib><creatorcontrib>OZAKI, TSUNEO</creatorcontrib><creatorcontrib>NAKAMURA, YUKIO</creatorcontrib><creatorcontrib>IWASHITA, MITSUTOSHI</creatorcontrib><title>Predicting sperm retrieval rates in testicular sperm extraction for azoospermia according to endocrine profiles</title><title>Reproductive medicine and biology</title><addtitle>Reprod Med Biol</addtitle><description>Background and Aims: The present study was carried out to examine the predictive value of endocrine profiles as indicators of the sperm retrieval rate on testicular sperm extraction (TESE) in azoospermic men.
Methods: Prior to TESE, the serum levels of follicle stimulating hormone (FSH), luteinizing hormone (LH), prolactin, testosterone, dihydrotestosterone (DHT), estradiol and 17 α‐hydroxyprogesterone were measured and the sagittal cross‐sections of the testis were acquired using ultrasonography.
Results: The sperm retrieval rates according to the cause of azoospermia were 40% for idiopathic azoospermia, and 100% for obstructive azoospermia, cryptorchidsm and ejaculatory disorder. Based on the endocrinological profiles, the sperm retrieval rates showed significant differences at 100% for FSH 15 mIU/mL or LH 2 mIU/mL, 0% for FSH > 60 mIU/mL or LH > 12 mIU/mL, and 33% for the intermediate groups (P < 0.01). Comparison of the retrieval of spermatozoa and serum DHT level for the intermediate group also showed a significant difference, with retrieval rates of 58% for DHT 0.5 ng/mL and 0% for DHT > 0.5 ng/mL (P < 0.01).
Conclusions: The etiology, serum FSH, LH and DHT levels are useful in predicting the sperm retrieval rates on TESE in azoospermic patients. (Reprod Med Biol 2005; 4: 239–245)</description><subject>17β-Estradiol</subject><subject>Andrology</subject><subject>azoospermia</subject><subject>Dihydrotestosterone</subject><subject>endocrinology</subject><subject>etiology</subject><subject>Follicle-stimulating hormone</subject><subject>Follicles</subject><subject>In vitro fertilization</subject><subject>Luteinizing hormone</subject><subject>Ovaries</subject><subject>Prolactin</subject><subject>Serum levels</subject><subject>Sperm</subject><subject>sperm retrieval rate</subject><subject>Testes</subject><subject>testicular sperm extraction</subject><subject>Testosterone</subject><subject>Urology</subject><issn>1445-5781</issn><issn>1447-0578</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqNkU1rFEEQhgcxmBj9C9LgxcuM_T1bIIKG-AERRfTc9PbUxF5mu9fumbjJr7dnd7OoJ-tSBfXUS1W9VUUYbViJl6uGSdnWVLWLhlOqGkoZE832QXV2bDzc1aouJTutHue8KlALkj-qTjlozQXIsyp-Sdh5N_pwTfIG05okHJPHGzuQZEfMxAdS0ujdNNh0YHA7JluGYiB9TMTexbhreEusczF1s9wYCYYuuuQDkk2KvR8wP6lOejtkfHrI59X3d5ffLj7UV5_ff7x4c1U7qUHUFkQLTNFOKXBWQA9OcsUBtOA9w75fAm0VgKLaAvKlRMkWWoIUiuulBHFevd7rbqblGjuHoWw8mE3ya5tuTbTe_N0J_oe5jjdGLYC1ihWBFweBFH9O5QFm7bPDYbAB45QNp1xLzstKBX3-D7qKUwrlPCNoeTTlUreFWuwpl2LOCfvjMoya2VWzMrN5ZjbPzK6anatmW0af_XnMcfDexgK82gO_yo9v_1vYfP30thTiNwqqsg4</recordid><startdate>200512</startdate><enddate>200512</enddate><creator>JINNO, MASAO</creator><creator>OZAKI, TSUNEO</creator><creator>NAKAMURA, YUKIO</creator><creator>IWASHITA, MITSUTOSHI</creator><general>Blackwell Science Pty</general><general>John Wiley & Sons, Inc</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8FE</scope><scope>8FH</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>LK8</scope><scope>M7P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>200512</creationdate><title>Predicting sperm retrieval rates in testicular sperm extraction for azoospermia according to endocrine profiles</title><author>JINNO, MASAO ; OZAKI, TSUNEO ; NAKAMURA, YUKIO ; IWASHITA, MITSUTOSHI</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4693-a9379150d559ca39f9c425299632f1effb907599506a9e2b4e41864943526b493</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>17β-Estradiol</topic><topic>Andrology</topic><topic>azoospermia</topic><topic>Dihydrotestosterone</topic><topic>endocrinology</topic><topic>etiology</topic><topic>Follicle-stimulating hormone</topic><topic>Follicles</topic><topic>In vitro fertilization</topic><topic>Luteinizing hormone</topic><topic>Ovaries</topic><topic>Prolactin</topic><topic>Serum levels</topic><topic>Sperm</topic><topic>sperm retrieval rate</topic><topic>Testes</topic><topic>testicular sperm extraction</topic><topic>Testosterone</topic><topic>Urology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>JINNO, MASAO</creatorcontrib><creatorcontrib>OZAKI, TSUNEO</creatorcontrib><creatorcontrib>NAKAMURA, YUKIO</creatorcontrib><creatorcontrib>IWASHITA, MITSUTOSHI</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Biological Science Database</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Reproductive medicine and biology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>JINNO, MASAO</au><au>OZAKI, TSUNEO</au><au>NAKAMURA, YUKIO</au><au>IWASHITA, MITSUTOSHI</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Predicting sperm retrieval rates in testicular sperm extraction for azoospermia according to endocrine profiles</atitle><jtitle>Reproductive medicine and biology</jtitle><addtitle>Reprod Med Biol</addtitle><date>2005-12</date><risdate>2005</risdate><volume>4</volume><issue>4</issue><spage>239</spage><epage>245</epage><pages>239-245</pages><issn>1445-5781</issn><eissn>1447-0578</eissn><abstract>Background and Aims: The present study was carried out to examine the predictive value of endocrine profiles as indicators of the sperm retrieval rate on testicular sperm extraction (TESE) in azoospermic men.
Methods: Prior to TESE, the serum levels of follicle stimulating hormone (FSH), luteinizing hormone (LH), prolactin, testosterone, dihydrotestosterone (DHT), estradiol and 17 α‐hydroxyprogesterone were measured and the sagittal cross‐sections of the testis were acquired using ultrasonography.
Results: The sperm retrieval rates according to the cause of azoospermia were 40% for idiopathic azoospermia, and 100% for obstructive azoospermia, cryptorchidsm and ejaculatory disorder. Based on the endocrinological profiles, the sperm retrieval rates showed significant differences at 100% for FSH 15 mIU/mL or LH 2 mIU/mL, 0% for FSH > 60 mIU/mL or LH > 12 mIU/mL, and 33% for the intermediate groups (P < 0.01). Comparison of the retrieval of spermatozoa and serum DHT level for the intermediate group also showed a significant difference, with retrieval rates of 58% for DHT 0.5 ng/mL and 0% for DHT > 0.5 ng/mL (P < 0.01).
Conclusions: The etiology, serum FSH, LH and DHT levels are useful in predicting the sperm retrieval rates on TESE in azoospermic patients. (Reprod Med Biol 2005; 4: 239–245)</abstract><cop>Melbourne, Australia</cop><pub>Blackwell Science Pty</pub><pmid>29662394</pmid><doi>10.1111/j.1447-0578.2005.00113.x</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Reproductive medicine and biology, 2005-12, Vol.4 (4), p.239-245 |
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| language | eng |
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| subjects | 17β-Estradiol Andrology azoospermia Dihydrotestosterone endocrinology etiology Follicle-stimulating hormone Follicles In vitro fertilization Luteinizing hormone Ovaries Prolactin Serum levels Sperm sperm retrieval rate Testes testicular sperm extraction Testosterone Urology |
| title | Predicting sperm retrieval rates in testicular sperm extraction for azoospermia according to endocrine profiles |
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