Coccidioides immitis septic knee arthritis

A 78-year-old man developed right knee pain and swelling without other systemic symptoms. He had travelled frequently to the Central Valley of California. He was diagnosed with coccidioidomycosis based on joint fluid culture. Coccidioidal complement fixation antibody titres were extremely elevated....

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Veröffentlicht in:	BMJ case reports 2018-03, Vol.2018, p.bcr-2017-222585
1. Verfasser:	Weisenberg, Scott A
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antifungal agents Antifungal Agents - therapeutic use Arthralgia - diagnostic imaging Arthralgia - microbiology Arthralgia - physiopathology Arthritis Arthritis, Infectious - drug therapy Arthritis, Infectious - microbiology Arthritis, Infectious - physiopathology Arthroscopy Case reports Coccidioides - isolation & purification Coccidioidomycosis - drug therapy Coccidioidomycosis - microbiology Coccidioidomycosis - physiopathology Debridement Disease Epidemiology Family medical history Humans Infections Itraconazole - therapeutic use Knee Knee Joint - diagnostic imaging Knee Joint - microbiology Magnetic Resonance Imaging Male Pain Patients Pneumonia Surgery Unusual Presentation of More Common Disease/Injury
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Beschreibung
Zusammenfassung:	A 78-year-old man developed right knee pain and swelling without other systemic symptoms. He had travelled frequently to the Central Valley of California. He was diagnosed with coccidioidomycosis based on joint fluid culture. Coccidioidal complement fixation antibody titres were extremely elevated. Arthroscopic debridement and fluconazole therapy did not lead to satisfactory improvement. Subsequent open debridement and change to itraconazole was followed by resolution of clinical signs of infection.
ISSN:	1757-790X 1757-790X
DOI:	10.1136/bcr-2017-222585