Long-Term Follow-up of Monoclonal Gammopathy of Undetermined Significance

Long-Term Follow-up of Monoclonal Gammopathy of Undetermined Significance

MGUS affects more than 5% of persons older than 70 years and shortens survival, as compared with age-matched controls. In a long-term study involving more than 1000 patients, those with IgM MGUS had a higher rate of progression to B-cell cancer than those with IgG MGUS.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:The New England journal of medicine 2018-01, Vol.378 (3), p.241-249
Hauptverfasser: Kyle, Robert A, Larson, Dirk R, Therneau, Terry M, Dispenzieri, Angela, Kumar, Shaji, Cerhan, James R, Rajkumar, S. Vincent
Format: Artikel
Sprache:eng
Schlagworte:
Benign monoclonal gammopathy
Immunoglobulin M
Immunoglobulins
Leukemia
Light chains
M protein
Medical disorders
Medical prognosis
Multiple myeloma
Patients
Risk factors
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:MGUS affects more than 5% of persons older than 70 years and shortens survival, as compared with age-matched controls. In a long-term study involving more than 1000 patients, those with IgM MGUS had a higher rate of progression to B-cell cancer than those with IgG MGUS.
ISSN:0028-4793
1533-4406
DOI:10.1056/NEJMoa1709974