Global Incidence and mortality of oesophageal cancer and their correlation with socioeconomic indicators temporal patterns and trends in 41 countries

Oesophageal cancers (adenocarcinomas [AC] and squamous cell carcinomas [SCC]) are characterized by high incidence/mortality in many countries. We aimed to delineate its global incidence and mortality, and studied whether socioeconomic development and its incidence rate were correlated. The age-stand...

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Veröffentlicht in:Scientific reports 2018-03, Vol.8 (1), p.4522-13, Article 4522
Hauptverfasser: Wong, Martin C. S., Hamilton, Willie, Whiteman, David C., Jiang, Johnny Y., Qiao, Youlin, Fung, Franklin D. H., Wang, Harry H. X., Chiu, Philip W. Y., Ng, Enders K. W., Wu, Justin C. Y., Yu, Jun, Chan, Francis K. L., Sung, Joseph J. Y.
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Sprache:eng
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Zusammenfassung:Oesophageal cancers (adenocarcinomas [AC] and squamous cell carcinomas [SCC]) are characterized by high incidence/mortality in many countries. We aimed to delineate its global incidence and mortality, and studied whether socioeconomic development and its incidence rate were correlated. The age-standardized rates (ASRs) of incidence and mortality of this medical condition in 2012 for 184 nations from the GLOBOCAN database; national databases capturing incidence rates, and the WHO mortality database were examined. Their correlations with two indicators of socioeconomic development were evaluated. Joinpoint regression analysis was used to generate trends. The ratio between the ASR of AC and SCC was strongly correlated with HDI (r = 0.535 [men]; r = 0.661 [women]) and GDP (r = 0.594 [men]; r = 0.550 [women], both p 
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-018-19819-8