Antimicrobial Resistance Gene Acquisition and Depletion Following Fecal Microbiota Transplantation for Recurrent Clostridium difficile Infection

Fecal microbiota transplantation (FMT) may be a novel approach to eliminate multidrug-resistant bacteria from the gut and to prevent future infections. Using whole metagenome sequencing data from 8 FMT donor-recipient pairs, we identified 37 and 95 antimicrobial resistance genes that were acquired b...

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Veröffentlicht in:Clinical infectious diseases 2018-01, Vol.66 (3), p.456-457
Hauptverfasser: Leung, Victor, Vincent, Caroline, Edens, Thaddeus J, Miller, Mark, Manges, Amee R
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container_issue 3
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container_title Clinical infectious diseases
container_volume 66
creator Leung, Victor
Vincent, Caroline
Edens, Thaddeus J
Miller, Mark
Manges, Amee R
description Fecal microbiota transplantation (FMT) may be a novel approach to eliminate multidrug-resistant bacteria from the gut and to prevent future infections. Using whole metagenome sequencing data from 8 FMT donor-recipient pairs, we identified 37 and 95 antimicrobial resistance genes that were acquired by or removed from FMT recipients, respectively.
doi_str_mv 10.1093/cid/cix821
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source Jstor Complete Legacy; Oxford University Press Journals All Titles (1996-Current); Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection
subjects Antiinfectives and antibacterials
Antimicrobial agents
Antimicrobial resistance
Brief Reports
Drug resistance
Fecal microflora
Feces
Genes
Gram-positive bacteria
Medical procedures
Microbiota
Multidrug resistance
Recurrent infection
Transplantation
title Antimicrobial Resistance Gene Acquisition and Depletion Following Fecal Microbiota Transplantation for Recurrent Clostridium difficile Infection
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