Depressive symptom profiles, cardio-metabolic risk and inflammation: Results from the MIDUS study

Highlights • Depressive symptoms can be highly heterogeneous. • We identified empirically derived depressive symptom profiles. • Four subgroups were identified. • The Mild and Moderate Symptoms subgroups have higher cardiometabolic risk. • Inflammation attenuated these associations.

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Bibliographische Detailangaben
Veröffentlicht in:	Psychoneuroendocrinology 2017-08, Vol.82, p.17-25
Hauptverfasser:	Chirinos, Diana A., Ph.D, Murdock, Kyle W., Ph.D, LeRoy, Angie S., M.A, Fagundes, Christopher, Ph.D
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Affect Aged Anxiety - diagnosis Anxiety - etiology Biomarkers - blood Blood pressure Comorbidity Cross-Sectional Studies - methods Depression Depression - complications Depression - diagnosis Depression - etiology Depressive Disorder - diagnosis Depressive Disorder - etiology Endocrinology & Metabolism Female Heart Diseases - complications Heart Diseases - diagnosis Heart Diseases - etiology Humans Hyperglycemia Inflammation Inflammation - complications Inflammation - metabolism Latent class analysis Lipoproteins Male Metabolic syndrome Metabolic Syndrome - diagnosis Metabolic Syndrome - epidemiology Middle Aged Obesity Psychiatry Risk Factors Severity of Illness Index Surveys and Questionnaires United States - epidemiology
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Beschreibung
Zusammenfassung:	Highlights • Depressive symptoms can be highly heterogeneous. • We identified empirically derived depressive symptom profiles. • Four subgroups were identified. • The Mild and Moderate Symptoms subgroups have higher cardiometabolic risk. • Inflammation attenuated these associations.
ISSN:	0306-4530 1873-3360
DOI:	10.1016/j.psyneuen.2017.04.011