Antidiarrheal Activity of 80% Methanolic Leaf Extract of Justicia schimperiana

Antidiarrheal Activity of 80% Methanolic Leaf Extract of Justicia schimperiana

Background. Diarrhea is one of the leading causes of preventable death in developing countries and mainly affects children and infants. It has been reported that the leaf of Justicia schimperiana is used as an antidiarrheal agent in Libo Kemekem district, northwest Ethiopia. Method. The 80% methanol...

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Veröffentlicht in:Evidence-based complementary and alternative medicine 2018-01, Vol.2018 (2018), p.1-10
Hauptverfasser: Mekonnen, Belay, Wubneh, Zewdu Birhanu, Asrie, Assefa Belay
Format: Artikel
Sprache:eng
Schlagworte:
Alternative medicine
Antimicrobial agents
Castor oil
Charcoal
Children
Defecation
Developing countries
Diarrhea
Drug resistance
Gastric motility
Health aspects
Herbal medicine
Infants
Intestine
LDCs
Leaves
Medicine, Botanic
Medicine, Herbal
Pharmaceuticals
Pharmacology
Pharmacy
Phytochemicals
Tropical diseases
Weight reduction
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Zusammenfassung:Background. Diarrhea is one of the leading causes of preventable death in developing countries and mainly affects children and infants. It has been reported that the leaf of Justicia schimperiana is used as an antidiarrheal agent in Libo Kemekem district, northwest Ethiopia. Method. The 80% methanolic leaf extract of J. schimperiana was evaluated for its activity against castor oil-induced diarrhea, enteropooling, and gastrointestinal motility in mice. Results. Significant reduction (p
ISSN:1741-427X
1741-4288
DOI:10.1155/2018/3037120