Effect of chronic exercise on fluoride metabolism in fluorosis-susceptible mice exposed to high fluoride

The present study investigated the effect of chronic exercise on fluoride (F) metabolism in fluorosis-susceptible mice exposed to high-F and explored the relationship between F concentrations in bone and plasma. Thirty male mice were randomised into three groups: Group I (No-F, No-Exercise), Group I...

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Veröffentlicht in:	Scientific reports 2018-02, Vol.8 (1), p.3211-7, Article 3211
Hauptverfasser:	Amaral, Sandra L., Azevedo, Liane B., Buzalaf, Marilia A. R., Fabricio, Mayara F., Fernandes, Mileni S., Valentine, Ruth A., Maguire, Anne, Zohoori, Fatemeh V.
Format:	Artikel
Sprache:	eng
Schlagworte:	64/60 692/700/2814 692/700/3032/3086/3090 Animals Body weight Body Weight - drug effects Bone and Bones - chemistry Experiments Fluorides Fluorides - blood Fluorides - metabolism Fluorides - pharmacology Fluorosis Fluorosis, Dental Humanities and Social Sciences Male Metabolism Mice multidisciplinary Physical Conditioning, Animal - physiology Physical Functional Performance Plasma Science Science (multidisciplinary)
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Zusammenfassung:	The present study investigated the effect of chronic exercise on fluoride (F) metabolism in fluorosis-susceptible mice exposed to high-F and explored the relationship between F concentrations in bone and plasma. Thirty male mice were randomised into three groups: Group I (No-F, No-Exercise), Group II (50 ppmF, No-Exercise), Group III (50 ppmF, Exercise). Body weight and physical performance of all mice were measured at baseline and end of experiment. F concentrations of plasma and bone were measured at the end of experiment. Mean plasma F concentration was significantly higher (p
ISSN:	2045-2322 2045-2322
DOI:	10.1038/s41598-018-21616-2