Structural evaluation of the peritubular sheath of rat’s testes after administration of ribavirin: A possible impact on the testicular function

Structural evaluation of the peritubular sheath of rat’s testes after administration of ribavirin: A possible impact on the testicular function

Effects of ribavirin on the structure of peritubular sheath (PS) of seminiferous tubules and on testicular functions were studied. We found that ribavirin at a dose of 4 mg/kg/day for 4 weeks produced a significant reduction in testosterone level (6.3 ± 0.2; P 

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Veröffentlicht in:International journal of immunopathology and pharmacology 2017-09, Vol.30 (3), p.282-296
Hauptverfasser: Almasry, Shaima M, Hassan, Zeinab A, Elsaed, Wael M, Elbastawisy, Yasser M
Format: Artikel
Sprache:eng
Schlagworte:
Antiviral drugs
Apoptosis
Basement membranes
Collagen (type I)
Epithelium
Extracellular matrix
Germ cells
Original s
Ribavirin
Structure-function relationships
Testes
Testosterone
Tubules
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Zusammenfassung:Effects of ribavirin on the structure of peritubular sheath (PS) of seminiferous tubules and on testicular functions were studied. We found that ribavirin at a dose of 4 mg/kg/day for 4 weeks produced a significant reduction in testosterone level (6.3 ± 0.2; P 
ISSN:2058-7384
0394-6320
2058-7384
DOI:10.1177/0394632017726261