Urinary Bladder Mass Due To Chronic Lymphocytic Leukaemia

In summary, a predominant partially CD5-positive, kappa-restricted monoclonal B cell population was identified, immunophenotypically similar to that identified in previous bone marrow biopsy except that partial CD5 expression was identified. Complete blood count with differential At diagnosis End of...

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Veröffentlicht in:BMJ case reports 2018-01, Vol.2018, p.bcr-2017-223083
Hauptverfasser: Rai, Manoj P, Bedi, Prabhjot S, Marinas, Edwin B, Rayamajhi, Supratik
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Sprache:eng
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Zusammenfassung:In summary, a predominant partially CD5-positive, kappa-restricted monoclonal B cell population was identified, immunophenotypically similar to that identified in previous bone marrow biopsy except that partial CD5 expression was identified. Complete blood count with differential At diagnosis End of cycle 1 End of cycle 4 At progression White blood cells (WBC) × 10 9 /L × 176 56.7 3.1 53.1 Red blood cells (RBC) × 10 6 /uL 1.11 2.79 4.05 3.72 Haemoglobin(Hb) g/dL 3.8 9.3 13.8 13.4 Haematocrit (Hct) % 14.6 29.4 40.3 39.3 Mean corpusular Volume (MCV) fL 132 105 100 106 Mean corpuscular hemoglobin (MCH) pg 34.2 33.3 34.1 36 Mean corpuscular hemoglobin concentration (MCHC) g/dL 26 31.6 34.2 34.1 Platelet Count × 10 9 /L 30 23 216 186 Neutrophils % 1.9 1.1 41.4 51.9 Lymphocytes % 96.4 97 32.2 27.4 Monocytes % 1.6 1.8 16.2 17.1 Eosinophils % 0.1 0.1 7.3 2.7 Basophils % 0 0 2.9 0.9 Absolute neutrophils × 10 9 /L 3.344 0.59 1.3 27.55 Absolute lymphocytes × 10 9 /L 169.66 54.98 1.01 14.5 Absolute monocytes × 10 9 /L 2.816 1.02 0.51 9.08 Absolute eosinophils × 10 9 /L 0.176 0.08 0.23 1.4 Absolutebasophils × 10 9 /L 0 0.02 0.09 0.4 Figure 1; Intravenous contrast-enhanced CT in nephrographic phase showing enhancing mass in urinary bladder. Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the international workshop on chronic lymphocytic leukemia updating the national cancer institute-working group 1996 guidelines.
ISSN:1757-790X
1757-790X
DOI:10.1136/bcr-2017-223083