Prevalence of Abnormal Pap Smears: A Descriptive Study from a Cancer Center in a Low-Prevalence Community
Background and aims: Cervical cancer is the fourth most common cancer in women worldwide and the 13th in Jordan. The cervical smear (Pap smear) is a simple approach to detect pre-cancerous cervical lesions. The aim of this study was to evaluate the prevalence of abnormal cervical smears in women see...
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Veröffentlicht in: | Asian Pacific journal of cancer prevention : APJCP 2017-11, Vol.18 (11), p.3117-3121 |
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Sprache: | eng |
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Zusammenfassung: | Background and aims: Cervical cancer is the fourth most common cancer in women worldwide and the 13th in
Jordan. The cervical smear (Pap smear) is a simple approach to detect pre-cancerous cervical lesions. The aim of this
study was to evaluate the prevalence of abnormal cervical smears in women seen at the Early Detection/Community
Outreach clinic of King Hussein Cancer Center (KHCC). Materials and Methods: In this retrospective study, reports
of routine cervical Pap smears performed in the pathology department at KHCC from January 2007 to December
2016, were reviewed. During this period, a total of 5,529 routine smears were assessed for epithelial abnormalities and
histopathological grading. Results: A total of 210 (3.8%) abnormal Pap smears were found, with atypical squamous
cell of undetermined significance (ASC-US) reported in 110 (52.4%) cases, atypical glandular cells of undermined
significance (AGUS) in 58 (27.6%), low grade squamous intra-epithelial lesion (LSIL) in 27 (12.9%) and high grade
intra-epithelial lesion (HSIL) in 13 (6.2%). Only single cases of ASC-H and squamous cell carcinoma were reported.
The available biopsies showed benign findings in 70.1% of cases, low grade squamous intraepithelial lesions in 11.5%
and high grade squamous intraepithelial lesions in 18.4%. Conclusions: The low epithelial cell abnormality (EPCA)
prevalence illustrated in this study argues against introduction of population-based HPV testing and vaccination. It
calls for a more cost-effective measures in a country with limited resources, where a more widely available Pap-smear
testing might suffice. |
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ISSN: | 1513-7368 2476-762X |
DOI: | 10.22034/APJCP.2017.18.11.3117 |