Prevalence and Contributors to Low‐grade Inflammation in Three U.S. Populations of Reproductive Age Women

Background Inflammation, measured by high‐sensitivity C‐reactive protein (hsCRP), is linked to adverse reproductive outcomes. However, prevalence and predictors of low‐grade inflammation are poorly understood among reproductive age women. Therefore, the current aim was to characterize: (i) the preva...

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Veröffentlicht in:Paediatric and perinatal epidemiology 2018-01, Vol.32 (1), p.55-67
Hauptverfasser: Sjaarda, Lindsey A., Radin, Rose G., Swanson, Chandra, Kuhr, Daniel L., Mumford, Sunni L., Galai, Noya, Silver, Robert M., Wactawski‐Wende, Jean, Perkins, Neil J., Schisterman, Enrique F.
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Sprache:eng
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Zusammenfassung:Background Inflammation, measured by high‐sensitivity C‐reactive protein (hsCRP), is linked to adverse reproductive outcomes. However, prevalence and predictors of low‐grade inflammation are poorly understood among reproductive age women. Therefore, the current aim was to characterize: (i) the prevalence of elevated hsCRP and (ii) whether the association of various demographic, anthropometric, life style, and metabolic characteristics with higher hsCRP varies across populations of reproductive age women with varying risk profiles for adverse reproductive outcomes. Methods Bivariate analysis of characteristics among women ages 18–40 having hsCRP
ISSN:0269-5022
1365-3016
DOI:10.1111/ppe.12409