Systematic analysis of the regulatory roles of microRNAs in postnatal maturation and metergasis of liver of breeder cocks

Systematic analysis of the regulatory roles of microRNAs in postnatal maturation and metergasis of liver of breeder cocks

The liver function of chickens is intensively remodeled from birth to adult, which was validated by metabolomics research in the present study. In order to understand the roles of microRNAs (miRNA) in liver maturation and metergasis, miRNA expression profiles in livers of 20 male chicks aged one day...

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Veröffentlicht in:Scientific reports 2018-01, Vol.8 (1), p.61-61, Article 61
Hauptverfasser: Wu, Shengru, Guo, Wei, Liang, Saisai, Lu, Hong, Sun, Wenqiang, Ren, Xiaochun, Sun, Qingzhu, Yang, Xiaojun
Format: Artikel
Sprache:eng
Schlagworte:
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Birth
Cell cycle
Gene expression
Genomes
Humanities and Social Sciences
Juveniles
Liver
Maturation
Metabolomics
MicroRNAs
miRNA
mRNA
multidisciplinary
Science
Science (multidisciplinary)
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Zusammenfassung:The liver function of chickens is intensively remodeled from birth to adult, which was validated by metabolomics research in the present study. In order to understand the roles of microRNAs (miRNA) in liver maturation and metergasis, miRNA expression profiles in livers of 20 male chicks aged one day and five adult cocks aged 35 weeks were determined. A total of 191 differentially expressed miRNAs with the criteria of P 1.5 or
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-017-18674-3