IntOGen-mutations identifies cancer drivers across tumor types
IntOGen-mutations is a discovery tool for cancer researchers to find driver mutations in genes and pathways. The IntOGen-mutations platform ( http://www.intogen.org/mutations/ ) summarizes somatic mutations, genes and pathways involved in tumorigenesis. It identifies and visualizes cancer drivers, a...
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Veröffentlicht in: | Nature methods 2013-11, Vol.10 (11), p.1081-1082 |
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Hauptverfasser: | , , , , , , , |
Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | IntOGen-mutations is a discovery tool for cancer researchers to find driver mutations in genes and pathways.
The IntOGen-mutations platform (
http://www.intogen.org/mutations/
) summarizes somatic mutations, genes and pathways involved in tumorigenesis. It identifies and visualizes cancer drivers, analyzing 4,623 exomes from 13 cancer sites. It provides support to cancer researchers, aids the identification of drivers across tumor cohorts and helps rank mutations for better clinical decision-making. |
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ISSN: | 1548-7091 1548-7105 1548-7105 |
DOI: | 10.1038/nmeth.2642 |