Cancer Evolution during Immunotherapy

Cancer Evolution during Immunotherapy

Immune checkpoint blockade has revolutionized cancer treatment. In this issue of Cell, insights from a longitudinal multi-omics analysis of the largest yet-reported cohort of melanoma patients reveal how tumor and immunity co-evolve during anti-PD-1 therapy. Immune checkpoint blockade has revolution...

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Veröffentlicht in:Cell 2017-11, Vol.171 (4), p.740-742
Hauptverfasser: Andrews, M.C., Wargo, J.A.
Format: Artikel
Sprache:eng
Schlagworte:
cohort studies
disease control
Humans
Immunity
Immunotherapy
longitudinal studies
Melanoma
Nivolumab
patients
Programmed Cell Death 1 Receptor
Tumor Microenvironment
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Zusammenfassung:Immune checkpoint blockade has revolutionized cancer treatment. In this issue of Cell, insights from a longitudinal multi-omics analysis of the largest yet-reported cohort of melanoma patients reveal how tumor and immunity co-evolve during anti-PD-1 therapy. Immune checkpoint blockade has revolutionized cancer treatment. In this issue of Cell, insights from a longitudinal multi-omics analysis of the largest yet-reported cohort of melanoma patients reveal how tumor and immunity co-evolve during anti-PD-1 therapy.
ISSN:0092-8674
1097-4172
DOI:10.1016/j.cell.2017.10.027