Corneal densitometry after photorefractive keratectomy, laser-assisted in situ keratomileusis, and small-incision lenticule extraction
Purpose The aim of this study was to gain greater insight into the corneal densitometry changes occurring as a result of refractive surgery and to compare these changes across three widely used surgical techniques, namely, photorefractive keratectomy (PRK), laser-assisted in situ keratomileusis with...
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| Veröffentlicht in: | Eye (London) 2017-12, Vol.31 (12), p.1647-1654 |
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| creator | Poyales, F Garzón, N Mendicute, J Illarramendi, I Caro, P Jáñez, O Argüeso, F López, A |
| description | Purpose
The aim of this study was to gain greater insight into the corneal densitometry changes occurring as a result of refractive surgery and to compare these changes across three widely used surgical techniques, namely, photorefractive keratectomy (PRK), laser-assisted
in situ
keratomileusis with a femtosecond laser (LASIK-FS), or ReLEx small-incision lenticule extraction (ReLEx SMILE).
Patients and methods
Three hundred and thirty-six patients (184 male and 152 female patients) participated in this study. They were split into three groups according to the refractive surgery technique they had undergone: LASIK-FS (74 patients), PRK (153 patients), and ReLEx SMILE (109 patients). All participants underwent an exhaustive eye examination both before and after surgery. Pre- and postoperative corneal densitometry was measured using an Oculus Pentacam system.
Results
The mean postoperative total corneal densitometry values were 16.53±1.94 for the LASIK-FS group, 15.53±1.65 for PRK, and 16.10±1.54 for ReLEx SMILE. When corneal densitometry was analyzed for specific corneal areas, the values corresponding to the 0–2, 2–6, and 6–10 mm annuli were similar across the three surgical techniques. The only region in which differences were found was the peripheral area (
P |
| doi_str_mv | 10.1038/eye.2017.107 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5733279</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1910798988</sourcerecordid><originalsourceid>FETCH-LOGICAL-c450t-91b7d6693d163b346239b95ece1a0c5e81ac0f7949c60f980877a8768151f5ff3</originalsourceid><addsrcrecordid>eNptkU1rFTEUhoMo9lrduZaAGxd3aj5m8rERysWqUHCj4C7kZs60qZnkmmSK9w_4u5t6a6niKhze57w557wIvaTkhBKu3sIeThihslXyEVrRXopu6If-MVoRPZCOMfbtCD0r5YqQJkryFB0xJRjjVKzQr03KEWzAI8Tia5qh5j22U4WMd5eppgxTtq76a8DfIdsKrkH7NQ62QO5sKb5UGLGPuLUvBybNPsDSlDW2ccRltiF0PjpffIo4QKzeLQEw_Ky_vVN8jp5MNhR4cfceo69n779sPnbnnz982pyed64fSO003cpRCM1HKviW94JxvdUDOKCWuAEUtY5MUvfaCTJpRZSUVkmh6ECnYZr4MXp38N0t2xlG10bJNphd9rPNe5OsN38r0V-ai3RtBsk5k7oZvLkzyOnHAqWa2RcHIdgIaSmG6haDVlqphr7-B71KS45tvUZJ0RNBGW3U-kC5nEpp174fhhJzG7BpAZvbgFslG_7q4QL38J9EG9AdgNKkeAH5wa__M7wBbYq0Xg</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1976406121</pqid></control><display><type>article</type><title>Corneal densitometry after photorefractive keratectomy, laser-assisted in situ keratomileusis, and small-incision lenticule extraction</title><source>SpringerLink Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><creator>Poyales, F ; Garzón, N ; Mendicute, J ; Illarramendi, I ; Caro, P ; Jáñez, O ; Argüeso, F ; López, A</creator><creatorcontrib>Poyales, F ; Garzón, N ; Mendicute, J ; Illarramendi, I ; Caro, P ; Jáñez, O ; Argüeso, F ; López, A</creatorcontrib><description>Purpose
The aim of this study was to gain greater insight into the corneal densitometry changes occurring as a result of refractive surgery and to compare these changes across three widely used surgical techniques, namely, photorefractive keratectomy (PRK), laser-assisted
in situ
keratomileusis with a femtosecond laser (LASIK-FS), or ReLEx small-incision lenticule extraction (ReLEx SMILE).
Patients and methods
Three hundred and thirty-six patients (184 male and 152 female patients) participated in this study. They were split into three groups according to the refractive surgery technique they had undergone: LASIK-FS (74 patients), PRK (153 patients), and ReLEx SMILE (109 patients). All participants underwent an exhaustive eye examination both before and after surgery. Pre- and postoperative corneal densitometry was measured using an Oculus Pentacam system.
Results
The mean postoperative total corneal densitometry values were 16.53±1.94 for the LASIK-FS group, 15.53±1.65 for PRK, and 16.10±1.54 for ReLEx SMILE. When corneal densitometry was analyzed for specific corneal areas, the values corresponding to the 0–2, 2–6, and 6–10 mm annuli were similar across the three surgical techniques. The only region in which differences were found was the peripheral area (
P
<0.05), but these variations across techniques were not statistically significant.
Conclusions
Corneal densitometry can be used as an objective metric to assess corneal response to refractive surgery, and to monitor patients over time. Corneal densitometry was not negatively affected by any of the refractive surgical procedures under evaluation.</description><identifier>ISSN: 0950-222X</identifier><identifier>EISSN: 1476-5454</identifier><identifier>DOI: 10.1038/eye.2017.107</identifier><identifier>PMID: 28622316</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>692/308 ; 692/308/409 ; Clinical Study ; Cornea ; Densitometry ; Eye examinations ; Eye surgery ; Laboratory Medicine ; Lasers ; Medicine ; Medicine & Public Health ; Ophthalmology ; Pharmaceutical Sciences/Technology ; Statistical analysis ; Surgery ; Surgical Oncology ; Surgical techniques</subject><ispartof>Eye (London), 2017-12, Vol.31 (12), p.1647-1654</ispartof><rights>Macmillan Publishers Limited, part of Springer Nature. 2017</rights><rights>Copyright Nature Publishing Group Dec 2017</rights><rights>Copyright © 2017 Macmillan Publishers Limited, part of Springer Nature. 2017 Macmillan Publishers Limited, part of Springer Nature.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c450t-91b7d6693d163b346239b95ece1a0c5e81ac0f7949c60f980877a8768151f5ff3</citedby><cites>FETCH-LOGICAL-c450t-91b7d6693d163b346239b95ece1a0c5e81ac0f7949c60f980877a8768151f5ff3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733279/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733279/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,41464,42533,51294,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28622316$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Poyales, F</creatorcontrib><creatorcontrib>Garzón, N</creatorcontrib><creatorcontrib>Mendicute, J</creatorcontrib><creatorcontrib>Illarramendi, I</creatorcontrib><creatorcontrib>Caro, P</creatorcontrib><creatorcontrib>Jáñez, O</creatorcontrib><creatorcontrib>Argüeso, F</creatorcontrib><creatorcontrib>López, A</creatorcontrib><title>Corneal densitometry after photorefractive keratectomy, laser-assisted in situ keratomileusis, and small-incision lenticule extraction</title><title>Eye (London)</title><addtitle>Eye</addtitle><addtitle>Eye (Lond)</addtitle><description>Purpose
The aim of this study was to gain greater insight into the corneal densitometry changes occurring as a result of refractive surgery and to compare these changes across three widely used surgical techniques, namely, photorefractive keratectomy (PRK), laser-assisted
in situ
keratomileusis with a femtosecond laser (LASIK-FS), or ReLEx small-incision lenticule extraction (ReLEx SMILE).
Patients and methods
Three hundred and thirty-six patients (184 male and 152 female patients) participated in this study. They were split into three groups according to the refractive surgery technique they had undergone: LASIK-FS (74 patients), PRK (153 patients), and ReLEx SMILE (109 patients). All participants underwent an exhaustive eye examination both before and after surgery. Pre- and postoperative corneal densitometry was measured using an Oculus Pentacam system.
Results
The mean postoperative total corneal densitometry values were 16.53±1.94 for the LASIK-FS group, 15.53±1.65 for PRK, and 16.10±1.54 for ReLEx SMILE. When corneal densitometry was analyzed for specific corneal areas, the values corresponding to the 0–2, 2–6, and 6–10 mm annuli were similar across the three surgical techniques. The only region in which differences were found was the peripheral area (
P
<0.05), but these variations across techniques were not statistically significant.
Conclusions
Corneal densitometry can be used as an objective metric to assess corneal response to refractive surgery, and to monitor patients over time. Corneal densitometry was not negatively affected by any of the refractive surgical procedures under evaluation.</description><subject>692/308</subject><subject>692/308/409</subject><subject>Clinical Study</subject><subject>Cornea</subject><subject>Densitometry</subject><subject>Eye examinations</subject><subject>Eye surgery</subject><subject>Laboratory Medicine</subject><subject>Lasers</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Ophthalmology</subject><subject>Pharmaceutical Sciences/Technology</subject><subject>Statistical analysis</subject><subject>Surgery</subject><subject>Surgical Oncology</subject><subject>Surgical techniques</subject><issn>0950-222X</issn><issn>1476-5454</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNptkU1rFTEUhoMo9lrduZaAGxd3aj5m8rERysWqUHCj4C7kZs60qZnkmmSK9w_4u5t6a6niKhze57w557wIvaTkhBKu3sIeThihslXyEVrRXopu6If-MVoRPZCOMfbtCD0r5YqQJkryFB0xJRjjVKzQr03KEWzAI8Tia5qh5j22U4WMd5eppgxTtq76a8DfIdsKrkH7NQ62QO5sKb5UGLGPuLUvBybNPsDSlDW2ccRltiF0PjpffIo4QKzeLQEw_Ky_vVN8jp5MNhR4cfceo69n779sPnbnnz982pyed64fSO003cpRCM1HKviW94JxvdUDOKCWuAEUtY5MUvfaCTJpRZSUVkmh6ECnYZr4MXp38N0t2xlG10bJNphd9rPNe5OsN38r0V-ai3RtBsk5k7oZvLkzyOnHAqWa2RcHIdgIaSmG6haDVlqphr7-B71KS45tvUZJ0RNBGW3U-kC5nEpp174fhhJzG7BpAZvbgFslG_7q4QL38J9EG9AdgNKkeAH5wa__M7wBbYq0Xg</recordid><startdate>20171201</startdate><enddate>20171201</enddate><creator>Poyales, F</creator><creator>Garzón, N</creator><creator>Mendicute, J</creator><creator>Illarramendi, I</creator><creator>Caro, P</creator><creator>Jáñez, O</creator><creator>Argüeso, F</creator><creator>López, A</creator><general>Nature Publishing Group UK</general><general>Nature Publishing Group</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20171201</creationdate><title>Corneal densitometry after photorefractive keratectomy, laser-assisted in situ keratomileusis, and small-incision lenticule extraction</title><author>Poyales, F ; Garzón, N ; Mendicute, J ; Illarramendi, I ; Caro, P ; Jáñez, O ; Argüeso, F ; López, A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c450t-91b7d6693d163b346239b95ece1a0c5e81ac0f7949c60f980877a8768151f5ff3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>692/308</topic><topic>692/308/409</topic><topic>Clinical Study</topic><topic>Cornea</topic><topic>Densitometry</topic><topic>Eye examinations</topic><topic>Eye surgery</topic><topic>Laboratory Medicine</topic><topic>Lasers</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Ophthalmology</topic><topic>Pharmaceutical Sciences/Technology</topic><topic>Statistical analysis</topic><topic>Surgery</topic><topic>Surgical Oncology</topic><topic>Surgical techniques</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Poyales, F</creatorcontrib><creatorcontrib>Garzón, N</creatorcontrib><creatorcontrib>Mendicute, J</creatorcontrib><creatorcontrib>Illarramendi, I</creatorcontrib><creatorcontrib>Caro, P</creatorcontrib><creatorcontrib>Jáñez, O</creatorcontrib><creatorcontrib>Argüeso, F</creatorcontrib><creatorcontrib>López, A</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Neurosciences Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Eye (London)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Poyales, F</au><au>Garzón, N</au><au>Mendicute, J</au><au>Illarramendi, I</au><au>Caro, P</au><au>Jáñez, O</au><au>Argüeso, F</au><au>López, A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Corneal densitometry after photorefractive keratectomy, laser-assisted in situ keratomileusis, and small-incision lenticule extraction</atitle><jtitle>Eye (London)</jtitle><stitle>Eye</stitle><addtitle>Eye (Lond)</addtitle><date>2017-12-01</date><risdate>2017</risdate><volume>31</volume><issue>12</issue><spage>1647</spage><epage>1654</epage><pages>1647-1654</pages><issn>0950-222X</issn><eissn>1476-5454</eissn><abstract>Purpose
The aim of this study was to gain greater insight into the corneal densitometry changes occurring as a result of refractive surgery and to compare these changes across three widely used surgical techniques, namely, photorefractive keratectomy (PRK), laser-assisted
in situ
keratomileusis with a femtosecond laser (LASIK-FS), or ReLEx small-incision lenticule extraction (ReLEx SMILE).
Patients and methods
Three hundred and thirty-six patients (184 male and 152 female patients) participated in this study. They were split into three groups according to the refractive surgery technique they had undergone: LASIK-FS (74 patients), PRK (153 patients), and ReLEx SMILE (109 patients). All participants underwent an exhaustive eye examination both before and after surgery. Pre- and postoperative corneal densitometry was measured using an Oculus Pentacam system.
Results
The mean postoperative total corneal densitometry values were 16.53±1.94 for the LASIK-FS group, 15.53±1.65 for PRK, and 16.10±1.54 for ReLEx SMILE. When corneal densitometry was analyzed for specific corneal areas, the values corresponding to the 0–2, 2–6, and 6–10 mm annuli were similar across the three surgical techniques. The only region in which differences were found was the peripheral area (
P
<0.05), but these variations across techniques were not statistically significant.
Conclusions
Corneal densitometry can be used as an objective metric to assess corneal response to refractive surgery, and to monitor patients over time. Corneal densitometry was not negatively affected by any of the refractive surgical procedures under evaluation.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>28622316</pmid><doi>10.1038/eye.2017.107</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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| source | SpringerLink Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
| subjects | 692/308 692/308/409 Clinical Study Cornea Densitometry Eye examinations Eye surgery Laboratory Medicine Lasers Medicine Medicine & Public Health Ophthalmology Pharmaceutical Sciences/Technology Statistical analysis Surgery Surgical Oncology Surgical techniques |
| title | Corneal densitometry after photorefractive keratectomy, laser-assisted in situ keratomileusis, and small-incision lenticule extraction |
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