Clinicopathological characteristics and survival outcomes in pleomorphic lobular breast carcinoma of the breast: a SEER population‐based study

Clinicopathological characteristics and survival outcomes in pleomorphic lobular breast carcinoma of the breast: a SEER population‐based study

The purpose of this study was to explore the clinicopathological features and survival outcome of pleomorphic lobular carcinoma (PLC) of breast, we identified 131 PLC patients and 460,109 invasive ductal carcinoma (IDC) patients in the Surveillance, Epidemiology, and End Result (SEER) database. PLCs...

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Veröffentlicht in:Cancer medicine (Malden, MA) MA), 2017-12, Vol.6 (12), p.2867-2875
Hauptverfasser: Yang, Li‐Peng, Sun, He‐Fen, Zhao, Yang, Chen, Meng‐Ting, Zhang, Nong, Jin, Wei
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Adult
Age Factors
Aged
Aged, 80 and over
Breast cancer
Breast carcinoma
Breast Neoplasms - mortality
Breast Neoplasms - pathology
Breast Neoplasms - therapy
Carcinoma, Ductal, Breast - mortality
Carcinoma, Ductal, Breast - secondary
Carcinoma, Ductal, Breast - therapy
Carcinoma, Lobular - mortality
Carcinoma, Lobular - secondary
Carcinoma, Lobular - therapy
Chi-Square Distribution
Clinical Cancer Research
Disease Progression
Disease-Free Survival
Epidemiology
Humans
Invasive ductal carcinoma
Invasiveness
Kaplan-Meier Estimate
Lymph nodes
Lymphatic Metastasis
Medical prognosis
Metastases
Middle Aged
Multivariate Analysis
Neoplasm Grading
Neoplasm Invasiveness
Neoplasm Staging
Original Research
pleomorphic lobular cancer
Population studies
Population-based studies
Risk Factors
SEER
SEER Program
Survival
survival outcomes
Time Factors
Treatment Outcome
United States - epidemiology
Young Adult
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Zusammenfassung:The purpose of this study was to explore the clinicopathological features and survival outcome of pleomorphic lobular carcinoma (PLC) of breast, we identified 131 PLC patients and 460,109 invasive ductal carcinoma (IDC) patients in the Surveillance, Epidemiology, and End Result (SEER) database. PLCs presented with increased lymph node involvement, older age, higher AJCC stage and grade, and lower median survival months (PLC 84 ± 51.03 vs. IDC 105.2 ± 64.39 P 
ISSN:2045-7634
2045-7634
DOI:10.1002/cam4.1244