Alcohol, stem cells and cancer

Dosage, gender, and genetic susceptibility to the effects of alcohol remained only partially elucidated. In this review, we summarize the current knowledge of the mechanisms underlying the role of alcohol in liver and gastrointestinal cancers. In addition, two recent pathways- DNA repair and TGF-β s...

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Veröffentlicht in:	Genes & cancer 2017-09, Vol.8 (9-10), p.695-700
Hauptverfasser:	Gu, Shoujun, Nguyen, Bao-Ngoc, Rao, Shuyun, Li, Shulin, Shetty, Kirti, Rashid, Asif, Shukla, Vivek, Deng, Chu-Xia, Mishra, Lopa, Mishra, Bibhuti
Format:	Artikel
Sprache:	eng
Schlagworte:	Review
Online-Zugang:	Volltext
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Zusammenfassung:	Dosage, gender, and genetic susceptibility to the effects of alcohol remained only partially elucidated. In this review, we summarize the current knowledge of the mechanisms underlying the role of alcohol in liver and gastrointestinal cancers. In addition, two recent pathways- DNA repair and TGF-β signaling which provide new insights into alcohol in the regulation of cancers and stem cells are also discussed here.
ISSN:	1947-6019 1947-6027 1947-6027
DOI:	10.18632/genesandcancer.156