Detrimental effects of self-administered methamphetamine during pregnancy on offspring development in the rat

Detrimental effects of self-administered methamphetamine during pregnancy on offspring development in the rat

Highlights • Prenatal methamphetamine exposure is achieved via maternal iv self-administration. • Methamphetamine self-administration has no effect on pregnancy outcome. • Achievement of developmental milestones in exposed offspring is delayed.

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Bibliographische Detailangaben
Veröffentlicht in:Drug and alcohol dependence 2017-08, Vol.177, p.171-177
Hauptverfasser: Rüedi-Bettschen, Daniela, Platt, Donna M
Format: Artikel
Sprache:eng
Schlagworte:
Adults
Age
Animal model
Control methods
Dams
Delayed
Dosage
Drug abuse
Eruption
Eye
Females
Geotaxis
Gestation
Intrauterine exposure
Litter
Management
Maternal behavior
Methamphetamine
Neurodevelopment
Neurons
Offspring
Pregnancy
Prenatal exposure
Psychiatry
Rats
Recreational use
Righting reflex
Rodents
Saline solutions
Self-administration
Substance abuse
Weaning
Weight gain
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Beschreibung
Zusammenfassung:Highlights • Prenatal methamphetamine exposure is achieved via maternal iv self-administration. • Methamphetamine self-administration has no effect on pregnancy outcome. • Achievement of developmental milestones in exposed offspring is delayed.
ISSN:0376-8716
1879-0046
DOI:10.1016/j.drugalcdep.2017.03.042