Radiation therapy and serum salivary amylase in head and neck cancer

Radiation therapy and serum salivary amylase in head and neck cancer

Radiation therapy (RT) is a valid treatment option for head and neck cancer (HNC). The risk of RT-induced toxicities is significant, especially due to extended treatment fields. The raise in amylase activity is strictly dependent on the volume of salivary glands included in the irradiated target vol...

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Veröffentlicht in:Oncotarget 2017-10, Vol.8 (52), p.90496-90500
Hauptverfasser: Felice, Francesca De, Tombolini, Mario, Musella, Angela, Marampon, Francesco, Tombolini, Vincenzo, Musio, Daniela
Format: Artikel
Sprache:eng
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Review
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Zusammenfassung:Radiation therapy (RT) is a valid treatment option for head and neck cancer (HNC). The risk of RT-induced toxicities is significant, especially due to extended treatment fields. The raise in amylase activity is strictly dependent on the volume of salivary glands included in the irradiated target volume and it is firmly related to the dose. The aim of this review is to report the effects on salivary amylase activity after radiation exposure of salivary glands, in patients with HNC.
ISSN:1949-2553
1949-2553
DOI:10.18632/oncotarget.18763