Phase I/Ib study of olaparib and carboplatin in women with triple negative breast cancer

To investigate the safety, activity, and potential biomarkers of response to olaparib and carboplatin combination in sporadic triple negative breast cancer (TNBC). EXPERIMENTAL DESIGN: Metastatic or recurrent TNBC patients with no germline mutation or with BRCAPro scores

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Veröffentlicht in:Oncotarget 2017-10, Vol.8 (45), p.79175-79187
Hauptverfasser: Lee, Jung-Min, Hays, John L, Chiou, Victoria L, Annunziata, Christina M, Swisher, Elizabeth M, Harrell, Maria I, Yu, Minshu, Gordon, Nicolas, Sissung, Tristan M, Ji, Jiuping, Figg, William D, Minasian, Lori, Lipkowitz, Stanley, Wood, Bradford J, Doroshow, James, Kohn, Elise C
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Sprache:eng
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Zusammenfassung:To investigate the safety, activity, and potential biomarkers of response to olaparib and carboplatin combination in sporadic triple negative breast cancer (TNBC). EXPERIMENTAL DESIGN: Metastatic or recurrent TNBC patients with no germline mutation or with BRCAPro scores
ISSN:1949-2553
1949-2553
DOI:10.18632/oncotarget.16577