Neurobiological mechanisms of state-dependent learning

Neurobiological mechanisms of state-dependent learning

Highlights • SDL can be induced by a variety of endogenous and exogenous stimuli. • Many drugs supporting SDL converge on GABAergic transmission. • GABAergic induction of SDL is regulated by microRNAs. • SDL entails changes of circuit and global network activities. • SDL is a fundamental mechanism o...

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Veröffentlicht in:Current opinion in neurobiology 2017-08, Vol.45, p.92-98
Hauptverfasser: Radulovic, Jelena, Jovasevic, Vladimir, Meyer, Mariah AA
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Conditioning, Classical - physiology
Humans
Learning - physiology
Memory - physiology
MicroRNAs - metabolism
Neurobiology - trends
Neurology
Psychiatry
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Zusammenfassung:Highlights • SDL can be induced by a variety of endogenous and exogenous stimuli. • Many drugs supporting SDL converge on GABAergic transmission. • GABAergic induction of SDL is regulated by microRNAs. • SDL entails changes of circuit and global network activities. • SDL is a fundamental mechanism of learning and a gateway to psychopathology.
ISSN:0959-4388
1873-6882
DOI:10.1016/j.conb.2017.05.013