Hepatocyte-derived macrophage migration inhibitory factor mediates alcohol-induced liver injury in mice and patients

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Veröffentlicht in:	Journal of hepatology 2017-11, Vol.67 (5), p.1018-1025
Hauptverfasser:	Marin, Veronica, Poulsen, Kyle, Odena, Gemma, McMullen, Megan R, Altamirano, Jose, Sancho-Bru, Pau, Tiribelli, Claudio, Caballeria, Juan, Rosso, Natalia, Bataller, Ramon, E.Nagy, Laura
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcohol Alcoholic liver disease Animals Bone marrow Cell culture Cellular biology Central Nervous System Depressants - pharmacology Chimeras Cytokines Drug abuse Ethanol Ethanol - pharmacology Fatty liver Female Gastroenterology and Hepatology Gene expression Hepatitis Hepatocytes Hepatocytes - drug effects Hepatocytes - metabolism Humans Immunity, Innate Immunohistochemistry Inflammation Inflammation - immunology Innate immune system Leukocyte migration Liver - metabolism Liver - pathology Liver diseases Liver Diseases, Alcoholic - immunology Liver Diseases, Alcoholic - metabolism Liver Diseases, Alcoholic - pathology Localization Macrophage migration inhibitory factor Macrophage Migration-Inhibitory Factors - genetics Macrophage Migration-Inhibitory Factors - metabolism Male Mice Mice, Inbred C57BL Mice, Knockout MIF Migration inhibitory factor Mortality mRNA Myeloid cells Pathogenesis Patients Steatosis Translational research
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