Prognostic role of the neutrophil-to-lymphocyte ratio in patients with primary central nervous system lymphoma

Neutrophil-to-lymphocyte ratio (NLR) is one of the parameters of a complete blood cell count (CBC) test and has been reported to be an easily accessible prognostic marker in aggressive cancer, including non-Hodgkin lymphoma (NHL). Primary central nervous system lymphoma (PCNSL) is an extranodal NHL...

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Veröffentlicht in:Oncotarget 2017-09, Vol.8 (43), p.74975-74986
Hauptverfasser: Jung, Jongheon, Lee, Hyewon, Yun, Tak, Lee, Eunyoung, Moon, Hae, Joo, Jungnam, Park, Weon Seo, Choi, Mihong, Lee, Jeong-Ok, Lee, Jong Seok, Eom, Hyeon-Seok
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Sprache:eng
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Zusammenfassung:Neutrophil-to-lymphocyte ratio (NLR) is one of the parameters of a complete blood cell count (CBC) test and has been reported to be an easily accessible prognostic marker in aggressive cancer, including non-Hodgkin lymphoma (NHL). Primary central nervous system lymphoma (PCNSL) is an extranodal NHL with highly aggressive features. However, the importance of the NLR has never been assessed in PCNSL. This retrospective study enrolled 62 biopsy-proven patients whose baseline NLR was available, and reviewed their medical records to compare both high (≥2.0) and low NLR (
ISSN:1949-2553
1949-2553
DOI:10.18632/oncotarget.20480