Linking tuberous sclerosis complex, excessive mTOR signaling, and age-related neurodegeneration: a new association between TSC1 mutation and frontotemporal dementia

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Veröffentlicht in:	Acta neuropathologica 2017-11, Vol.134 (5), p.813-816
Hauptverfasser:	Olney, Nicholas T., Alquezar, Carolina, Ramos, Eliana Marisa, Nana, Alissa L., Fong, Jamie C., Karydas, Anna M., Taylor, Joanne B., Stephens, Melanie L., Argouarch, Andrea R., Van Berlo, Victoria A., Dokuru, Deepika R., Sherr, Elliott H., Jicha, Gregory A., Dillon, William P., Desikan, Rahul S., De May, Mary, Seeley, William W., Coppola, Giovanni, Miller, Bruce L., Kao, Aimee W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Correspondence Dementia Dementia disorders Frontotemporal dementia Frontotemporal Dementia - genetics Frontotemporal Dementia - metabolism Frontotemporal Dementia - pathology Humans Male Medicine Medicine & Public Health Middle Aged Mutation Neurodegeneration Neurosciences Pathology Signal Transduction - physiology TOR protein TOR Serine-Threonine Kinases - metabolism Tuberous sclerosis Tuberous Sclerosis - genetics Tuberous Sclerosis - metabolism Tuberous Sclerosis - pathology Tuberous Sclerosis Complex 1 Tuberous Sclerosis Complex 1 Protein Tumor Suppressor Proteins - genetics Tumor Suppressor Proteins - metabolism
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