ICSI significantly improved the pregnancy rate of patients with a high sperm DNA fragmentation index

ICSI significantly improved the pregnancy rate of patients with a high sperm DNA fragmentation index

Correlations between semen parameters and sperm DNA fragmentation index (DFI) were investigated to identify characteristics of sperm without DNA damage that could be used in selecting sperm for intracytoplasmic sperm injection (ICSI). Pregnancy outcomes were compared to determine whether fertilizati...

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Veröffentlicht in:Clinical and experimental reproductive medicine 2017-09, Vol.44 (3), p.132-140
Hauptverfasser: Chi, Hee-Jun, Kim, Seok-Gi, Kim, Youn-Young, Park, Ji-Young, Yoo, Chang-Seok, Park, Il-Hae, Sun, Hong-Gil, Kim, Jae-Won, Lee, Kyeong-Ho, Park, Hum-Dai
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Sprache:eng
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Zusammenfassung:Correlations between semen parameters and sperm DNA fragmentation index (DFI) were investigated to identify characteristics of sperm without DNA damage that could be used in selecting sperm for intracytoplasmic sperm injection (ICSI). Pregnancy outcomes were compared to determine whether fertilization (IVF) or ICSI is a better choice for patients who have sperm with a high-DFI. Semen analysis was carried out in 388 patients who visited our IVF center for the first time to investigate correlations between sperm DFI and semen parameters. In addition, 1,102 IVF cycles in 867 patients were carried out in the present study; 921 cycles in the low-DFI group (DFI
ISSN:2233-8233
2233-8241
DOI:10.5653/cerm.2017.44.3.132