Cardiometabolic Features of Polycystic Ovary Syndrome: Role of Androgens

Cardiometabolic Features of Polycystic Ovary Syndrome: Role of Androgens

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder that affects reproductive-age women. Hyperandrogenemia is present in a significant fraction (~80%) of women with PCOS. Increased prevalence of cardiometabolic risk factors is frequently observed in PCOS women. The present review...

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Veröffentlicht in:Physiology (Bethesda, Md.) Md.), 2017-09, Vol.32 (5), p.357-366
Hauptverfasser: Yanes Cardozo, Licy L, Romero, Damian G, Reckelhoff, Jane F
Format: Artikel
Sprache:eng
Schlagworte:
Androgens
Androgens - metabolism
Female
Heart - physiopathology
Humans
Hyperandrogenism - metabolism
Myocardium - metabolism
Polycystic ovary syndrome
Polycystic Ovary Syndrome - metabolism
Review
Risk factors
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Zusammenfassung:Polycystic ovary syndrome (PCOS) is the most common endocrine disorder that affects reproductive-age women. Hyperandrogenemia is present in a significant fraction (~80%) of women with PCOS. Increased prevalence of cardiometabolic risk factors is frequently observed in PCOS women. The present review aims to highlight the key role of androgens in mediating the negative cardiometabolic profile observed in PCOS women.
ISSN:1548-9213
1548-9221
DOI:10.1152/physiol.00030.2016