Primary Diffuse Large B-cell Lymphoma of the Breast: A Rare Case and Review of Literature

Hemoglobin of 11.9 g/dl, total leukocyte counts of 10,400/mm 3, platelet counts of 48,600/mm 3, serum creatinine of 0.72 mg/dl, alkaline phosphatase of 55 IU/L, serum glutamic pyruvic transaminase of 22 IU/L, serum glutamic oxaloacetic transaminase of 13 IU/L, total bilirubin levels of 0.88 mg/dl, serum albumin of 4.34 g/dl, lactate dehydrogenase (LDH) of 172 U/L, and serum uric acid of 4.52 mg/dl. Excisional biopsy performed showed atypical lymphocytic infiltration suspicious of non-Hodgkin's lymphoma (NHL) [Figure 1]. [1] PBL is defined as localized lymphoma to one or both breasts with or without regional lymph nodes such as ipsilateral axillary and/or supraclavicular lymph nodes. Impact of central nervous system (CNS) prophylaxis on the incidence and risk factors for CNS relapse in patients with diffuse large B-cell lymphoma treated in the rituximab era: A single centre experience and review of the literature.