Serum periostin is associated with type 2 immunity in severe asthma

Serum periostin is associated with type 2 immunity in severe asthma

Blood eosinophil percentage and counts per volume, sputum eosinophil percentage, Feno, and serum IgE levels were higher in patients with asthma than in healthy controls, but were not significantly different between patients with severe and nonsevere asthma (Table I). Because all these parameters are...

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Veröffentlicht in:Journal of allergy and clinical immunology 2016-06, Vol.137 (6), p.1904-1907.e2
Hauptverfasser: Johansson, Mats W., PhD, Evans, Michael D., MS, Crisafi, Gina M., BS, Holweg, Cécile T.J., PhD, Matthews, John G., MBBS, MRCP, PhD, Jarjour, Nizar N., MD
Format: Artikel
Sprache:eng
Schlagworte:
Allergy and Immunology
Asthma
Colleges & universities
Ethnicity
Neutrophils
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Zusammenfassung:Blood eosinophil percentage and counts per volume, sputum eosinophil percentage, Feno, and serum IgE levels were higher in patients with asthma than in healthy controls, but were not significantly different between patients with severe and nonsevere asthma (Table I). Because all these parameters are features of type 2 immunity,2 we determined a type 2 immunity composite score for the patients with asthma consisting of the 4 parameters blood eosinophil percentage, sputum eosinophil percentage, Feno, and IgE levels, as described in this article's Online Repository.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2015.12.1346