Pregnancy-induced changes in the pharmacokinetics of caffeine and its metabolites

This study sought to assess the pharmacokinetic (PK) changes of caffeine and its CYP1A2 metabolites across the 3 trimesters of pregnancy. A prospective, multicenter PK study was conducted among 59 pregnant women (93.2% white) who were studied once during a trimester. One beverage with 30‐95 mg caffe...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of clinical pharmacology 2016-05, Vol.56 (5), p.590-596
Hauptverfasser:	Yu, Tian, Campbell, Sarah C., Stockmann, Chris, Tak, Casey, Schoen, Katherine, Clark, Erin A. S., Varner, Michael W., Spigarelli, Michael G., Sherwin, Catherine M. T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Caffeine Caffeine - blood Caffeine - pharmacokinetics Caffeine - urine Cytochrome P-450 CYP1A2 - metabolism Female Humans Metabolism Metabolites pharmacokinetics Pregnancy Pregnancy - blood Pregnancy - metabolism Pregnancy - urine Pregnancy Trimesters - blood Pregnancy Trimesters - metabolism Pregnancy Trimesters - urine Theobromine - blood Theophylline - blood Urine Young Adult
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!