Amelioration of estrogen-deficiency-induced obesity by Ocimum gratissimum

Menopausal transition in women initiates with declining estrogen levels and is followed by significant changes in their physiological characteristics. These changes often lead to medical conditions, such as obesity, which is correlated with chronic low-grade/subclinical inflammation. L. is a food spice or traditional herb in many countries; the plant is rich in antioxidants, which possess anti-inflammation activities and multitude of other therapeutic functions. In this study, we evaluated effects of . extract (OGE) in preventing obesity by using ovariectomized (OVX) animal models to mimic menopausal women. OVX rats showed increase in body weight and in adipocyte size in perigonadal adipose tissue (