The prevalence and risk factors associated with osteoradionecrosis of the jaw in oral and oropharyngeal cancer patients treated with intensity-modulated radiation therapy (IMRT): The Memorial Sloan Kettering Cancer Center experience

Highlights • The prevalence of ORN in OCC & OPC patients treated with IMRT is 4.3%. • OPC patients are prone to develop ORN earlier compared to OCC patients. • High radiation dose, poor periodontal status and alcohol use are associated with ORN.

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Bibliographische Detailangaben
Veröffentlicht in:	Oral oncology 2017-01, Vol.64, p.44-51
Hauptverfasser:	Owosho, Adepitan A, Tsai, C. Jillian, Lee, Ryan S, Freymiller, Haley, Kadempour, Arvin, Varthis, Spyridon, Sax, Adi Z, Rosen, Evan B, Yom, SaeHee K, Randazzo, Joseph, Drill, Esther, Riedel, Elyn, Patel, Snehal, Lee, Nancy Y, Huryn, Joseph M, Estilo, Cherry L
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Female Head and neck cancer Hematology, Oncology and Palliative Medicine Humans Intensity-modulated radiation therapy Jaw Diseases - etiology Male Middle Aged Mouth Neoplasms - radiotherapy Oral cancer Oropharyngeal cancer Oropharyngeal Neoplasms - radiotherapy Osteoradionecrosis Osteoradionecrosis - etiology Otolaryngology Prevalence Radiotherapy, Intensity-Modulated - adverse effects Retrospective Studies Risk Factors
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Zusammenfassung:	Highlights • The prevalence of ORN in OCC & OPC patients treated with IMRT is 4.3%. • OPC patients are prone to develop ORN earlier compared to OCC patients. • High radiation dose, poor periodontal status and alcohol use are associated with ORN.
ISSN:	1368-8375 1879-0593
DOI:	10.1016/j.oraloncology.2016.11.015